Alien Syndrome Master System box art

Sega Master System · Action / Shooter

Alien Syndrome

Certified classic Co-op

SystemSega Master System
Released1987
GenreAction, Shooter
DeveloperSEGA
PublisherSEGA
Players1–2 players (co-op)
CommitmentAn evening or two (Roughly 1–6 hours to see it through)
SeriesAlien Syndrome
LegacyCertified classic · legacy score 12

Alien Syndrome is an action game released in 1987 for the Sega Master System, developed by SEGA. It blends action and shooter elements.

It came out in the Master System's second year on the market. Other notable Master System releases from 1987 include Phantasy Star, Out Run and Alex Kidd: High-Tech World. Among the 64 Master System action games in our database, it ranks #3 by legacy score.

It is part of the Alien Syndrome series. The series also appears on other systems with Alien Syndrome (C64) and Alien Syndrome (NES). SEGA also made Alex Kidd in Miracle World, Phantasy Star and Hang-On for the Master System.

Alien Syndrome supports up to 2 players, including cooperative play, which makes it a strong pick for playing with a friend.

Pick it if…

  • you want to fight, blast and test your reflexes
  • you have time for an evening or two (roughly 1–6 hours to see it through)
  • you want a game to beat together with a friend
  • you want to experience one of the Master System's defining games

Maybe skip it if…

  • you prefer slow, thoughtful games over reflex tests

What playing Alien Syndrome is like

Action games test reflexes and nerve. Expect fast enemies, tight controls and stages you clear by reacting quickly and learning enemy patterns.

Tip for newcomers: Retro action games are often short but tough. Treat early deaths as practice runs; every attempt teaches you where the next threat comes from.

Alien Syndrome gameplay screenshot on Master System
In-game screenshot (Master System)

Alien Syndrome cheats & codes

13 codes on file (Action Replay, Other codes). Here are a few Action Replay codes to start with:

Infinite Lives00C0-5409
Unlimited Time00C0-7B06
Need One Hostage To Open Exit00C0-7501
Keep Flame Weapon00C8-ED01

See all Alien Syndrome cheats

Alien Syndrome walkthroughs & guides

Stuck, or want to go deeper? These trusted sites have full walkthroughs, completion times and more for Alien Syndrome.

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Playing Master System games today

The Master System library is full of colorful arcade-style games that are easy to pick up. Many titles also appear in Sega's official compilations.

Alien Syndrome FAQ

When did Alien Syndrome come out on the Master System?

Alien Syndrome was released for the Sega Master System in 1987.

Who made Alien Syndrome?

It was developed by SEGA.

Is Alien Syndrome multiplayer?

Yes. Alien Syndrome supports up to 2 players, including co-op play.

How long does Alien Syndrome take to play?

As an action game, Alien Syndrome typically falls into the "An evening or two" category: roughly 1–6 hours to see it through. Your time will vary with skill and how much you explore.

Read more about Alien Syndrome on Wikipedia. Facts on this page are compiled from the open libretro database and Wikidata; "legacy score" reflects how widely a game is documented across Wikipedia's language editions. Spotted an error? Let us know.

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