Dr. Mario 64 N64 box art

Nintendo 64 · Puzzle

Dr. Mario 64

SystemNintendo 64
Released2001
GenrePuzzle
DeveloperNewcom
PublisherNintendo
Players1–4 players
CommitmentQuick session (Under an hour, or endless arcade fun)
SeriesDr. Mario
LegacyWell-known · legacy score 12

Released for the Nintendo 64 in 2001, Dr. Mario 64 is a puzzle game developed by Newcom and published by Nintendo.

It landed about 5 years into the N64's life. Other notable N64 releases from 2001 include Conker's Bad Fur Day, Tony Hawk's Pro Skater 2 and Aidyn Chronicles: The First Mage. Among the 10 N64 puzzle games in our database, it ranks #2 by legacy score.

It is part of the Dr. Mario series. The series also appears on other systems with 2 Games in 1: Dr. Mario + Puzzle League (GBA) and 2 Games in One!: Dr. Mario + Puzzle League (GBA).

Dr. Mario 64 supports up to 4 players, whether that means taking turns or going head-to-head.

Pick it if…

  • you want to think and plan
  • you have time for a quick session (under an hour, or endless arcade fun)
  • you have a friend to play against

Maybe skip it if…

  • you want story, exploration or action

What playing Dr. Mario 64 is like

Puzzle games challenge pattern recognition, planning and quick thinking, from falling-block games to single-screen logic puzzles.

Tip for newcomers: Puzzle games are perfect for short sessions and often have endless or score-attack modes, so they never really end.

Dr. Mario 64 gameplay screenshot on N64
In-game screenshot (N64)

Dr. Mario 64 cheats & codes

43 codes on file (GameShark). Here are a few GameShark codes to start with:

Enable Code (M)F100D2E0 2400
P1 Dual ActivatorD101D804 0000
P1 Activator 1D001D804 0000
P1 Activator 2D001D805 0000
P2 Dual ActivatorD101D80C 0000
P2 Activator 1D001D80C 0000

See all Dr. Mario 64 cheats

Dr. Mario 64 walkthroughs & guides

Stuck, or want to go deeper? These trusted sites have full walkthroughs, completion times and more for Dr. Mario 64.

If you like Dr. Mario 64, the Matrix also picks…

Wetrix box art
Wetrix N64 · 1998 · Puzzle Deep cut

Playing N64 games today

The N64 is at its best with friends on the couch: its library is packed with four-player party, racing and shooter games. Selected titles are available through Nintendo Switch Online + Expansion Pack.

Dr. Mario 64 FAQ

When did Dr. Mario 64 come out on the N64?

Dr. Mario 64 was released for the Nintendo 64 in 2001.

Who made Dr. Mario 64?

It was developed by Newcom and published by Nintendo.

Is Dr. Mario 64 multiplayer?

Yes. Dr. Mario 64 supports up to 4 players.

How long does Dr. Mario 64 take to play?

As a puzzle game, Dr. Mario 64 typically falls into the "Quick session" category: under an hour, or endless arcade fun. Your time will vary with skill and how much you explore.

Read more about Dr. Mario 64 on Wikipedia. Facts on this page are compiled from the open libretro database and Wikidata; "legacy score" reflects how widely a game is documented across Wikipedia's language editions. Spotted an error? Let us know.

Not sure? Let the Matrix pick for you